Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885186 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2GLAALDH1A1CYP1A2POLB | |
| SCHEMBL8883577 | 0.85 | TAS1R3 (0.36) | CYP3A4ALOX5HDAC6TAS1R3TAS1R1 | |
| SCHEMBL8883095 | 0.84 | TAS1R3 (0.35) | CYP3A4ALOX5HDAC6TAS1R3TAS1R1 | |
| SCHEMBL8975870 | 0.80 | TAS1R3 (0.38) | CYP3A4ALOX5HDAC6TAS1R3TAS1R1 | |
| SCHEMBL8882405 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2GLAALDH1A1HTTTACR3 | |
| SCHEMBL8975448 | 0.78 | TAS1R3 (0.37) | CYP3A4ALOX5HDAC6TAS1R3TAS1R1 | |
| SCHEMBL4313304 | 0.76 | TACR3 (0.41) | ALDH1A1ALOX5TAS1R3TAS1R1TACR3 | |
| SCHEMBL31373087 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CYP1A2TAS1R3TAS1R1TACR3 | |
| SCHEMBL1897757 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CYP1A2TAS1R3TAS1R1TACR3 | |
| SCHEMBL8882408 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2GLAALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650513-A | Process for preparing perylene-3,4-dicarboxylic acid derivatives, the derivatives thus prepared and their use | CIBA-GEIGY CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |