SCHEMBL888268

SCHEMBL888268

CCCCC(C)(C)C(COCC)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
ZDHHC7 Q9NXF8 1/20 0.37
TSHR P16473 1/20 0.34
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
HSD17B10 Q99714 2/20 0.32
BIRC2 Q13490 2/20 0.31
ACHE P22303 1/20 0.30
ABCB1 P08183 1/20 0.30
HPGD P15428 1/20 0.30
RECQL P46063 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888534 0.89 CYP4F2 (0.37) CA1CA2MAPTMEN1KMT2A
SCHEMBL888503 0.87 CA1 (0.44) CA1CA2USP2LMNAZDHHC7
SCHEMBL818857 0.83 CA1 (0.35) CA1CA2USP2LMNAZDHHC7
SCHEMBL820481 0.82 ALDH1A1 (0.31) CYP4F2CYP4A11
SCHEMBL820260 0.79 CA1 (0.37) CA1CA2USP2LMNAZDHHC7
SCHEMBL888405 0.79 CYP4F2 (0.37) CA1CA2ZDHHC7TSHRMAPT
SCHEMBL20711118 0.77 CA1 (0.49) CA1CA2USP2LMNAZDHHC7
SCHEMBL888441 0.76 TSHR (0.37) CA1CA2USP2LMNAZDHHC7
SCHEMBL29010401 0.75 USP2 (0.55) CA1CA2USP2LMNAZDHHC7
SCHEMBL888389 0.75 TSHR (0.36) CA1CA2USP2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed