SCHEMBL888441

SCHEMBL888441

CCOCC(C(=O)OC)C(C)(C)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
MMP8 P22894 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
ZDHHC7 Q9NXF8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888351 0.87 ALDH1A1 (0.36) TSHRALDH1A1LMNATHRBMGAM
SCHEMBL820260 0.85 CA1 (0.37) TSHRALDH1A1CA1CA2USP2
SCHEMBL888422 0.84 CA1 (0.35) CA1CA2USP2LMNASMN1; SMN2
SCHEMBL818857 0.81 CA1 (0.35) TSHRALDH1A1CA1CA2USP2
SCHEMBL888389 0.80 TSHR (0.36) TSHRALDH1A1CA1CA2USP2
SCHEMBL819280 0.79 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL888625 0.77 ALDH1A1 (0.36) TSHRALDH1A1LMNAMGAMGAA
SCHEMBL888268 0.76 CA1 (0.42) TSHRCA1CA2USP2LMNA
SCHEMBL20995950 0.74 HSD17B10 (0.41) TSHRCA1CA2USP2LMNA
SCHEMBL838756 0.74 TSHR (0.39) TSHRALDH1A1CA1CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed