SCHEMBL888389

SCHEMBL888389

CCOCC(C(=O)OC)C(C)(C)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP8 P22894 1/20 0.33
CA12 O43570 1/20 0.32
CA14 Q9ULX7 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
PIK3CD O00329 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
METAP2 P50579 1/20 0.30
METAP1 P53582 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888627 0.87 MMP8 (0.34) TSHRMMP8LMNAALDH1A1MGAM
SCHEMBL820260 0.83 CA1 (0.37) TSHRCA1CA2MMP8CA12
SCHEMBL888640 0.83 SMN1; SMN2 (0.34) CA1CA2CA12CA14SMN1; SMN2
SCHEMBL818857 0.80 CA1 (0.35) TSHRCA1CA2MMP8SMN1; SMN2
SCHEMBL888441 0.80 TSHR (0.37) TSHRCA1CA2MMP8SMN1; SMN2
SCHEMBL819988 0.80
SCHEMBL888339 0.76 MMP8 (0.34) MMP8SMN1; SMN2LMNAALDH1A1MGAM
SCHEMBL888268 0.75 CA1 (0.42) TSHRCA1CA2SMN1; SMN2USP2
SCHEMBL444073 0.72 TSHR (0.42) TSHRCA1CA2CA12CA14
SCHEMBL10272288 0.72 TSHR (0.42) TSHRCA1CA2CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed