Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 8/20 | 0.53 |
| ▸ | THRA | P10827 | 7/20 | 0.53 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 2/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883017 | 0.89 | THRA (0.63) | THRBTHRAHAO1KMT2AMEN1 | |
| SCHEMBL8769358 | 0.88 | PLK1 (0.57) | NPC1RAB9ATHRBTHRAHAO1 | |
| SCHEMBL8882509 | 0.85 | RARB (0.47) | THRBTHRAHAO1PLK1PLK3 | |
| SCHEMBL3043815 | 0.83 | THRB (0.68) | SMN1; SMN2THRBTHRAKMT2AMEN1 | |
| SCHEMBL7930197 | 0.83 | THRB (0.68) | SMN1; SMN2THRBTHRAKMT2AMEN1 | |
| SCHEMBL8086401 | 0.83 | THRB (0.68) | SMN1; SMN2THRBTHRAKMT2AMEN1 | |
| SCHEMBL1248565 | 0.83 | THRB (0.68) | SMN1; SMN2THRBTHRAKMT2AMEN1 | |
| SCHEMBL8080349 | 0.83 | THRB (0.68) | SMN1; SMN2THRBTHRAKMT2AMEN1 | |
| SCHEMBL8072596 | 0.83 | THRB (0.68) | SMN1; SMN2THRBTHRAKMT2AMEN1 | |
| SCHEMBL7931204 | 0.83 | PLK1 (0.55) | NPC1RAB9AKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595685-A | THIAZOLE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0439170-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0439170-A2 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-07-31 | — | — | EP | disclosed |