Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 10/20 | 0.63 |
| ▸ | THRB | P10828 | 10/20 | 0.63 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RARA | P10276 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769358 | 0.91 | PLK1 (0.57) | THRATHRBHAO1PLK1 | |
| SCHEMBL8883263 | 0.89 | NPC1 (0.54) | THRATHRBHAO1PLK1TRPV1 | |
| SCHEMBL8884118 | 0.88 | RARB (0.59) | THRATHRBHAO1PLK1TRPV1 | |
| SCHEMBL9215324 | 0.88 | RARB (0.59) | THRATHRBHAO1PLK1TRPV1 | |
| SCHEMBL28562555 | 0.86 | THRA (0.64) | THRATHRBHAO1PLK1TRPV1 | |
| SCHEMBL12638341 | 0.85 | SPHK1 (0.57) | THRATHRBHAO1PLK1TRPV1 | |
| SCHEMBL8947232 | 0.85 | PLK1 (0.55) | THRATHRBHAO1PLK1TRPV1 | |
| SCHEMBL15174084 | 0.85 | PLK1 (0.55) | THRATHRBHAO1PLK1TRPV1 | |
| SCHEMBL7931204 | 0.85 | PLK1 (0.55) | PLK1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9491031 | 0.84 | L3MBTL1 (0.71) | THRATHRBPLK1RARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595685-A | THIAZOLE DERIVATIVE | CANON KABUSHIKI KAISHA (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0439170-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0439170-A2 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-07-31 | — | — | EP | disclosed |