SCHEMBL88833

SCHEMBL88833

c1cc2occc2cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29813261 1.00
SCHEMBL15971546 0.98 DYRK1A (0.50)
SCHEMBL8660682 0.85 DYRK1A (0.41)
SCHEMBL10824 0.81
Isoquinoline SCHEMBL10682580 0.80 DYRK1A (0.43)
SCHEMBL32685371 0.77
SCHEMBL30422679 0.77 DYRK1A (0.49)
SCHEMBL31692910 0.73 ALDH1A1 (0.38)
SCHEMBL8274131 0.73 DRD1 (0.45)
SCHEMBL30826357 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4611899-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP claimed
US-20250075265-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS ROCHE SEQUENCING SOLUTIONS INC (US) 2025-03-06 US claimed
CN-115103835-B IL-17A modulators and uses thereof 戴斯阿尔法公司 2024-12-10 CN claimed
CN-116284019-B Preparation method of medical intermediate furo [3,2-c ] pyridine-4 (5H) -ketone derivative 安徽工业大学 2024-08-09 CN claimed
US-20240182460-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PETRA PHARMA CORPORATION 2024-06-06 US claimed
WO-2024097172-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PETRA PHARMA CORPORATION (US) 2024-05-10 WO claimed
US-11970731-B2 Enhancement of nucleic acid polymerization by aromatic compounds Roche Sequencing Solutions, Inc. (US) 2024-04-30 US claimed
EP-4347040-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF CANCER Petra Pharma Corporation (US) 2024-04-10 EP claimed
CN-117769546-A Allosteric ketene inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease 佩特拉制药公司 2024-03-26 CN claimed
US-11878970-B2 Allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) for the treatment of disease PETRA PHARMA CORPORATION (US) 2024-01-23 US claimed
WO-2004016604-A2 AZABICYCLIC COMPOUNDS ARE CENTRAL NERVOUS SYSTEM ACTIVE AGENTS ABBOTT LABORATORIES (US) 2004-02-26 WO claimed
WO-2003037904-A1 NOVEL 3BETA-AMINO AZABICYCLOOCTANE HETEROAROMATIC AMIDE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USES THEREOF PIERRE FABRE MEDICAMENT (FR) 2003-05-08 WO claimed
WO-2001070728-A1 2-[NITROGEN-HETEROCYCLIC]PYRIMIDONE DERIVATIVES SANOFI-SYNTHELABO (FR) 2001-09-27 WO claimed
EP-0236880-B1 Penem derivatives ERBA CARLO SPA (IT) 1994-07-20 EP claimed
US-5206365-A Psychotropic heterobicycloalkylpiperazine derivatives NEW JAMES S (US) 1993-04-27 US claimed
US-5116970-A Tranquilizers NEW JAMES S (US) 1992-05-26 US claimed
US-5001130-A 1-((Amide-containing bicyclic hetero ring)-butyl-),4-heterocyclic-piperazine; anxiolytic agents; psychological disorders BRISTOL-MYERS COMPANY (US) 1991-03-19 US claimed
US-4886793-A PENICILLINS; HUMANS OR ANIMALS FARMITALIA CARLO ERBA, S.R.L. (IT) 1989-12-12 US claimed
EP-0236880-A2 Penem derivatives FARMITALIA CARLO ERBA S.r.l. (IT) 1987-09-16 EP claimed
US-4406898-A ANTIBIOTICS CONTAINING A THIENOPYRIDINIUM OR FUROPYRIDINIUM GROUP ELI LILLY AND COMPANY (US) 1983-09-27 US claimed