Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884505 | 0.88 | COXFA4 (0.48) | COXFA4HPGDTP53ALDH1A1HIF1A | |
| SCHEMBL8885457 | 0.86 | COXFA4 (0.47) | COXFA4HPGDTP53ALDH1A1HIF1A | |
| SCHEMBL8882898 | 0.85 | COXFA4 (0.48) | COXFA4TP53HIF1AEPAS1NPC1 | |
| SCHEMBL8885308 | 0.83 | MAPT (0.61) | COXFA4HIF1AEPAS1KMT2AMEN1 | |
| SCHEMBL8882813 | 0.82 | MEN1 (0.52) | COXFA4HPGDHIF1AKMT2AMEN1 | |
| SCHEMBL8884738 | 0.81 | COXFA4 (0.48) | COXFA4HPGDTP53ALDH1A1KMT2A | |
| SCHEMBL8885313 | 0.81 | NPC1 (0.52) | COXFA4HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL11398330 | 0.80 | COXFA4 (0.62) | COXFA4HPGDTP53ALDH1A1HIF1A | |
| SCHEMBL8884548 | 0.80 | NPC1 (0.58) | COXFA4HPGDTP53ALDH1A1KMT2A | |
| SCHEMBL8883913 | 0.80 | HSP90AA1 (0.51) | COXFA4HPGDALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677324-A | MUSCLE RELAXANTS | PFIZER INC. (US) | 1997-10-14 | — | — | US | disclosed |
| EP-0690855-B1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LTD (GB) | 1996-12-18 | — | — | EP | disclosed |
| WO-1994020491-A1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |