Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884278 | 0.89 | RAB9A (0.55) | MAPTSMN1; SMN2RAB9ANPC1COXFA4 | |
| SCHEMBL8882853 | 0.87 | NPC1 (0.56) | SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL8884766 | 0.86 | RAB9A (0.51) | MAPTSMN1; SMN2RAB9ANPC1COXFA4 | |
| SCHEMBL8883383 | 0.83 | COXFA4 (0.52) | MAPTSMN1; SMN2RAB9ANPC1COXFA4 | |
| SCHEMBL8882813 | 0.82 | MEN1 (0.52) | MAPTRAB9ANPC1COXFA4KMT2A | |
| SCHEMBL8884505 | 0.81 | COXFA4 (0.48) | MAPTSMN1; SMN2RAB9ANPC1COXFA4 | |
| SCHEMBL8885313 | 0.81 | NPC1 (0.52) | SMN1; SMN2RAB9ANPC1COXFA4KMT2A | |
| SCHEMBL8883913 | 0.80 | HSP90AA1 (0.51) | SMN1; SMN2RAB9ANPC1COXFA4KDM4E | |
| SCHEMBL8885457 | 0.80 | COXFA4 (0.47) | MAPTSMN1; SMN2RAB9ANPC1COXFA4 | |
| SCHEMBL30874650 | 0.80 | COXFA4 (0.53) | MAPTSMN1; SMN2RAB9ANPC1COXFA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677324-A | MUSCLE RELAXANTS | PFIZER INC. (US) | 1997-10-14 | — | — | US | disclosed |
| EP-0690855-B1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LTD (GB) | 1996-12-18 | — | — | EP | disclosed |
| WO-1994020491-A1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |