SCHEMBL888353

SCHEMBL888353

CCOC(CC(C)C)C(C(=O)Cl)C1CCCC1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 3/20 0.34
MMP8 P22894 1/20 0.34
ADAM17 P78536 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.32
GAA P10253 1/20 0.32
ALOX15 P16050 1/20 0.32
MMP9 P14780 2/20 0.32
MMP14 P50281 2/20 0.32
EPHX1 P07099 2/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
ALDH1A1 P00352 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888466 0.98 MMP1 (0.34) MMP1MMP8ADAM17SMN1; SMN2GAA
SCHEMBL888463 0.86 ALDH1A1 (0.41) MMP1MMP8ADAM17SMN1; SMN2GAA
SCHEMBL888424 0.85 ALDH1A1 (0.43) MMP1MMP8ADAM17SMN1; SMN2GAA
SCHEMBL819473 0.77 ALDH1A1 (0.33) MMP1EPHX1MMP2ALDH1A1NPSR1
SCHEMBL819084 0.76 ALDH1A1 (0.35) MMP1EPHX1MMP2ALDH1A1NPSR1
SCHEMBL820724 0.73 LMNA (0.36)
SCHEMBL10876120 0.70 ATM (0.42) EPHX1MMP2ALDH1A1
SCHEMBL13269664 0.70 ALDH1A1 (0.43) MMP1MMP8ADAM17SMN1; SMN2GAA
SCHEMBL820722 0.69 LMNA (0.32)
SCHEMBL13269026 0.69 ALDH1A1 (0.45) MMP1MMP8ADAM17SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288488-B2 Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed