Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890310 | 0.89 | MRGPRX4 (0.52) | MAOBP2RY12CYP2C9CYP2C19MRGPRX4 | |
| SCHEMBL8885039 | 0.88 | RXRA (0.58) | RXRARXRBNPC1RAB9AMRGPRX4 | |
| SCHEMBL8881676 | 0.87 | PPIA (0.49) | RXRARXRBMAOBNPC1RAB9A | |
| SCHEMBL8885115 | 0.86 | MAOB (0.54) | RXRARXRBMAOBNPC1RAB9A | |
| SCHEMBL8883579 | 0.86 | MAOB (0.48) | RXRARXRBMAOBL3MBTL1CYP2C9 | |
| SCHEMBL8883498 | 0.86 | MAOB (0.48) | RXRARXRBMAOBP2RY12CYP2C9 | |
| SCHEMBL8883630 | 0.85 | RXRA (0.45) | RXRARXRBNPC1RAB9AMRGPRX4 | |
| SCHEMBL8882407 | 0.83 | MAOB (0.62) | RXRARXRBMAOBCYP2C9CYP2C19 | |
| SCHEMBL8885505 | 0.83 | RXRA (0.43) | RXRARXRBNPC1RAB9AMRGPRX4 | |
| SCHEMBL8881837 | 0.83 | MAOB (0.53) | RXRARXRBMAOBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658933-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |