SCHEMBL888370

SCHEMBL888370

CCCCCC(COC)(C(=O)OC)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
EPHX1 P07099 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
ACAT1 P24752 1/20 0.34
SOAT1 P35610 1/20 0.34
CES2 O00748 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
PRSS1 P07477 1/20 0.32
CTSG P08311 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888556 0.95 CA1 (0.34) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL888570 0.87 LMNA (0.36) CYP3A4TSHRLMNA
SCHEMBL888477 0.87 MEN1 (0.45) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL819808 0.83 ALDH1A1 (0.34) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL888484 0.81 CYP4F2 (0.40) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL6873127 0.81 MEN1 (0.47) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL888454 0.80 DGAT1 (0.34)
SCHEMBL818621 0.77 ALDH1A1 (0.33) TP53TSHRCA1CA2LMNA
SCHEMBL6873197 0.74 MEN1 (0.57) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL888298 0.74 CYP4F2 (0.39) MAPTMEN1KMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed