SCHEMBL888392

SCHEMBL888392

CCOC(=O)C(C(OCC)C(C)(C)C)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
HSD17B10 Q99714 2/20 0.34
LMNA P02545 1/20 0.34
ALOX15 P16050 3/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
MMP8 P22894 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
CPB2 Q96IY4 1/20 0.32
TRPA1 O75762 1/20 0.31
CYP3A4 P08684 2/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
CHRM1 P11229 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888621 0.87 ALDH1A1 (0.32) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL232519 0.83 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL819440 0.80
SCHEMBL14770006 0.79 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL13821863 0.79 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL15034664 0.79 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL888612 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL27622649 0.75 ALDH1A1 (0.39) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL888408 0.74 MMP8 (0.36) ALDH1A1HSD17B10LMNAMMP8
SCHEMBL1787405 0.73 ALDH1A1 (0.37) ALDH1A1HSD17B10LMNAALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed