SCHEMBL888408

SCHEMBL888408

CCOC(=O)C(C(CC(C)C)OCC)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.36
ALDH1A1 P00352 3/20 0.34
LMNA P02545 2/20 0.34
HSD17B10 Q99714 1/20 0.34
HPGD P15428 1/20 0.30
PPID Q08752 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888529 0.87 MMP8 (0.34) MMP8ALDH1A1LMNAHSD17B10
SCHEMBL820722 0.83 LMNA (0.32) LMNA
SCHEMBL13821863 0.77 ALDH1A1 (0.46) MMP8ALDH1A1LMNAHSD17B10HPGD
SCHEMBL14770006 0.77 ALDH1A1 (0.46) MMP8ALDH1A1LMNAHSD17B10HPGD
SCHEMBL15034664 0.77 ALDH1A1 (0.46) MMP8ALDH1A1LMNAHSD17B10HPGD
SCHEMBL232519 0.77 ALDH1A1 (0.46) MMP8ALDH1A1LMNAHSD17B10
SCHEMBL888601 0.77 ALDH1A1 (0.38) MMP8ALDH1A1LMNAHSD17B10HPGD
SCHEMBL888392 0.74 ALDH1A1 (0.36) MMP8ALDH1A1LMNAHSD17B10
SCHEMBL818211 0.73 LMNA (0.30) LMNA
SCHEMBL1787405 0.72 ALDH1A1 (0.37) MMP8ALDH1A1LMNAHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed