SCHEMBL1488786

SCHEMBL1488786

CNCCN(C(C)C)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.48
CARM1 Q86X55 1/20 0.48
PRMT6 Q96LA8 1/20 0.48
PRMT1 Q99873 1/20 0.48
PRMT8 Q9NR22 1/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.36
SIGMAR1 Q99720 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25604363 0.87 PRMT3 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL24744949 0.85 MEN1 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL9493744 0.83 MEN1 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL24912449 0.83 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL13996765 0.81 MEN1 (0.40) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL5932747 0.79 MEN1 (0.48) MEN1KMT2AALDH1A1SIGMAR1BCHE
SCHEMBL26350120 0.78 PRMT3 (0.34) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL25633209 0.77 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL25594688 0.75 MEN1 (0.36) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL24693233 0.75 PRMT3 (0.32) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. 2024-07-04 US disclosed
US-11911483-B2 Modified self-immolating moieties for use in prodrugs and conjugates and methods of using and making BRISTOL-MYERS SQUIBB COMPANY (US) 2024-02-27 US disclosed
US-11911483-B2 Modified self-immolating moieties for use in prodrugs and conjugates and methods of using and making BRISTOL-MYERS SQUIBB COMPANY (US) 2024-02-27 US disclosed
US-20230399343-A1 PROCESS OF MAKING CFTR MODULATORS VERTEX PHARMACEUTICALS (SAN DIEGO) LLC 2023-12-14 US disclosed
US-20230310485-A1 POLYNUCLEOTIDE AGENTS TARGETING ANGIOTENSINOGEN (AGT) AND METHODS OF USE THEREOF ALNYLAM PHARMACEUTICALS, INC. 2023-10-05 US disclosed
US-20230293706-A1 Multicomponent Delivery Systems for Polyanionic Cargo Compound Delivery MEDICI THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230285581-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2023-09-14 US disclosed
EP-3640248-B1 AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) 2023-08-23 EP disclosed
EP-3640248-B1 AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) 2023-08-23 EP disclosed
US-11696953-B2 Poly(beta-amino esters) and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-07-11 US disclosed
US-5530127-A AMINATION OF PRIMARY OR SECONDARY ALCOHOL IN PRESENCE OF ZIRCONIUM/COPPER/NICKEL OXIDE CATALYST, ALSO CONTAINING MOLYBDENUM AND POSSIBLE ALUMINUM AND MANGANESE BASF AKTIENGESELLSCHAFT (DE) 1996-06-25 US disclosed
EP-0696572-A1 Process for the preparation of amines BASF AKTIENGESELLSCHAFT (DE) 1996-02-14 EP disclosed
CN-1106405-A Trisubstituted pyrimido [5,4-d] pyrimidines for modulating THOMAE GMBH DR K (DE) 1995-08-09 CN disclosed
US-5348953-A Elastase inhibitor MERCK & CO., INC. (US) 1994-09-20 US disclosed
WO-1994013636-A1 NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS MERCK & CO., INC. (US) 1994-06-23 WO disclosed
US-5236956-A Compounds for the treatment of urinary incontinence KABI PHARMACIA AKTIEBOLAG (SE) 1993-08-17 US disclosed
EP-0367040-B1 COMPOUNDS FOR THE TREATMENT OF URINARY INCONTINENCE Kabi Pharmacia AB (SE) 1993-04-21 EP disclosed
EP-0525973-A2 Substituted azetidinones as anti-inflammatory and antidegenerative agents MERCK & CO. INC. (US) 1993-02-03 EP disclosed
WO-1993000332-A1 SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS MERCK & CO., INC. (US) 1993-01-07 WO disclosed
EP-0367040-A1 Compounds for the treatment of urinary incontinence Kabi Pharmacia AB (SE) 1990-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11911483-B2 Modified self-immolating moieties for use in prodrugs and conjugates and methods of using and making PAICS, UGT1A1, CYP7A1 PRMT3 1423/4885CARM1 1354/4885PRMT6 1310/4885
US-20230399343-A1 PROCESS OF MAKING CFTR MODULATORS CFTR, SLC26A4, TMEM109 PRMT3 3661/4885CARM1 3175/4885PRMT6 3462/4885
US-20230310485-A1 POLYNUCLEOTIDE AGENTS TARGETING ANGIOTENSINOGEN (AGT) AND METHODS OF USE THEREOF AGT, AGTR1, AGTR2 PRMT3 2957/4885CARM1 4661/4885PRMT6 2771/4885
US-20230293706-A1 Multicomponent Delivery Systems for Polyanionic Cargo Compound Delivery MTREX, EXOSC5, KPNA6 PRMT3 3962/4885CARM1 2458/4885PRMT6 2727/4885
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LIPA, NPC1L1, NPC1 PRMT3 4181/4885CARM1 3499/4885PRMT6 4452/4885
US-20230285581-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF ASGR1, CUTA, SRPRA PRMT3 3361/4885CARM1 4741/4885PRMT6 2671/4885
US-11696953-B2 Poly(beta-amino esters) and uses thereof BCAT1, BCAT2, SNRPE PRMT3 1882/4885CARM1 2364/4885PRMT6 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.