Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888429 | 0.86 | MTNR1A (0.51) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8883208 | 0.84 | MTNR1A (0.51) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL8884153 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL8892513 | 0.79 | MTNR1A (0.66) | MTNR1AMTNR1BHTR2CMEN1KMT2A | |
| SCHEMBL8884710 | 0.79 | MTNR1A (0.67) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8884977 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL9120459 | 0.76 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL8883211 | 0.74 | MTNR1A (0.54) | MTNR1AMTNR1BMAPTSMN1; SMN2 | |
| SCHEMBL8617176 | 0.74 | MTNR1A (0.54) | MTNR1AMTNR1BMAPT | |
| SCHEMBL8884998 | 0.72 | MTNR1A (0.64) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612368-A | SKIN DISORDERS, MELATONINERGIC SYSTEMS, ANTIARRHYTHMIA AGENTS OR ANTIISCHEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-03-18 | — | — | US | disclosed |