SCHEMBL888422

SCHEMBL888422

COCC(C(=O)OC)C(C)(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820133 0.84 SMN1; SMN2 (0.38) CA1CA2SMN1; SMN2USP2LMNA
SCHEMBL25493095 0.84 SMN1; SMN2 (0.38) CA1CA2SMN1; SMN2USP2LMNA
SCHEMBL888441 0.84 TSHR (0.37) CA1CA2SMN1; SMN2USP2LMNA
SCHEMBL888625 0.83 ALDH1A1 (0.36) LMNA
SCHEMBL820091 0.79 CA1 (0.37) CA1CA2SMN1; SMN2USP2LMNA
SCHEMBL888640 0.79 SMN1; SMN2 (0.34) CA1CA2SMN1; SMN2USP2LMNA
SCHEMBL10711245 0.78 CA1 (0.35) CA1CA2SMN1; SMN2USP2LMNA
SCHEMBL819977 0.78 ALDH1A1 (0.30)
SCHEMBL888503 0.74 CA1 (0.44) CA1CA2USP2LMNA
SCHEMBL839985 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed