SCHEMBL888640

SCHEMBL888640

COCC(C(=O)OC)C(C)(C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.34
CA14 Q9ULX7 3/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
PIK3CD O00329 1/20 0.33
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888339 0.85 MMP8 (0.34) SMN1; SMN2LMNA
SCHEMBL888389 0.83 TSHR (0.36) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL25493095 0.81 SMN1; SMN2 (0.38) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL820133 0.81 SMN1; SMN2 (0.38) SMN1; SMN2CA14CA12CA1CA2
SCHEMBL819723 0.80
SCHEMBL888422 0.79 CA1 (0.35) SMN1; SMN2CA14CA1CA2USP2
SCHEMBL820091 0.76 CA1 (0.37) SMN1; SMN2CA1CA2USP2LMNA
SCHEMBL10711245 0.75 CA1 (0.35) SMN1; SMN2CA14CA1CA2USP2
SCHEMBL888503 0.71 CA1 (0.44) CA1CA2USP2LMNA
SCHEMBL888627 0.69 MMP8 (0.34) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed