SCHEMBL8884359

SCHEMBL8884359

CC1CN1C(=O)c1cccc(N2CC2C)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
NPC1 O15118 1/20 0.47
HSD17B10 Q99714 1/20 0.46
GFER P55789 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPK1 P28482 2/20 0.40
PIK3CD O00329 1/20 0.40
LMNA P02545 3/20 0.40
USP2 O75604 1/20 0.40
MAPT P10636 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
TP53 P04637 1/20 0.39
L3MBTL3 Q96JM7 1/20 0.39
MAPK14 Q16539 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133281 0.86 HTT (0.60) HTTL3MBTL1NPC1HSD17B10MEN1
SCHEMBL1935843 0.86 HTT (0.60) HTTL3MBTL1NPC1HSD17B10MEN1
SCHEMBL583470 0.84 L3MBTL1 (0.41) HTTL3MBTL1NPC1HSD17B10GFER
SCHEMBL27894302 0.80 L3MBTL1 (0.55) HTTL3MBTL1NPC1HSD17B10MEN1
SCHEMBL3898423 0.80 HTT (0.76) HTTL3MBTL1NPC1HSD17B10LMNA
SCHEMBL14884897 0.80 HTT (0.55) HTTL3MBTL1HSD17B10MEN1KMT2A
SCHEMBL3887377 0.79 L3MBTL1 (0.54) HTTL3MBTL1HSD17B10
SCHEMBL3889485 0.79 ALDH1A1 (0.60) HTTL3MBTL1HSD17B10TSHRTP53
SCHEMBL3889887 0.79 PIK3CD (0.60) HTTL3MBTL1MAPK1PIK3CDLMNA
SCHEMBL252505 0.77 ACHE (0.55) HTTL3MBTL1PIK3CDTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150361307-A1 PRESSURE SENSITIVE ADHESIVE TAPE AND ARTICLES MADE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2015-12-17 US disclosed
US-5611825-A UREA-FORMALDEHYDE AND LATEX MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-18 US disclosed
EP-0747169-A2 Abrasive articles and methods of making same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-11 EP disclosed