SCHEMBL60160

SCHEMBL60160

CC(C)Cn1cnc2c(=O)[nH]c(=O)[nH]c21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.47
TLR7 Q9NYK1 4/20 0.40
POLB P06746 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PDE4D Q08499 2/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
LMNA P02545 1/20 0.35
HRH2 P25021 1/20 0.35
ADRA1D P25100 1/20 0.35
HTR2A P28223 1/20 0.35
ADORA2A P29274 1/20 0.35
ADRA1A P35348 1/20 0.35
NUDT1 P36639 1/20 0.35
HTR2B P41595 1/20 0.35
KCNH2 Q12809 1/20 0.35
GDA Q9Y2T3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7326970 0.88 PNP (0.48) PNPSMN1; SMN2LMNAHTR2AADORA2A
SCHEMBL3489068 0.87 PNP (0.44) PNPSMN1; SMN2LMNAGDAMEN1
SCHEMBL8884657 0.85 PNP (0.51) PNPNPC1RAB9ALMNAGDA
SCHEMBL380137 0.82 PNP (0.50) PNPSMN1; SMN2PDE4DPDE4APDE4B
SCHEMBL9386892 0.81 PNP (0.47) PNPSMN1; SMN2LMNAGDAMEN1
SCHEMBL7217325 0.81 PNP (0.49) PNPSMN1; SMN2PDE4DPDE4APDE4B
SCHEMBL4014481 0.80 PNP (0.46) PNPSMN1; SMN2LMNAMEN1KMT2A
SCHEMBL5054173 0.79 PNP (0.54) PNPPDE4DPDE4APDE4BPDE4C
SCHEMBL27573642 0.79 PNP (0.50) PNPSMN1; SMN2LMNAHTR2AGDA
SCHEMBL27586845 0.79 PNP (0.53) PNPSMN1; SMN2LMNAHTR2AGDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2446024-A1 MESENCHYMAL STEM CELLS GROWN UNDER HYPOXIC CONDITIONS: COMPOSITIONS, METHODS AND USES THEREFOR Life&Light Limited (GB) 2012-05-02 EP claimed
US-20100330047-A1 Mesenchymal Stem Cells Grown Under Hypoxic Conditions: Compositions, Methods and Uses Therefor LIFE & LIGHT LTD. (GB) 2010-12-30 US claimed
WO-2010150094-A1 MESENCHYMAL STEM CELLS GROWN UNDER HYPOXIC CONDITIONS: COMPOSITIONS, METHODS AND USES THEREFOR LIFE & LIGHT LIMITED (GB) 2010-12-29 WO claimed
WO-2010108008-A2 BSC CELL DIFFERENTIATION AND USE IN THERAPY UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) 2010-09-23 WO claimed
CN-1134537-C Separation, extracorporeal culture, preparation and application of human primitive mesenchymal stem cell population 四川轻化工学院 2004-01-14 CN claimed
CN-1287166-A Separation, extracorporeal culture, preparation and application of human primitive mesenchymal stem cell population HE QINGHUA (CN) 2001-03-14 CN claimed
US-12173323-B2 Methods of using PDX1-positive pancreatic endoderm cells and endocrine precursor cells VIACYTE, INC. (US) 2024-12-24 US disclosed
US-20240409900-A1 CELL ENCAPSULATION DEVICE COMPRISING A PANCREATIC PROGENITOR CELL POPULATION VIACYTE, INC. (US) 2024-12-12 US disclosed
US-20240220740-A1 AUTOMATIC CONSTRUCTION METHOD FOR PARALLEL CORPORA AND INFORMATION PROCESSING APPARATUS FUJITSU LIMITED (JP) 2024-07-04 US disclosed
EP-4394648-A1 PARALLEL CORPUS CONSTRUCTION PROGRAM, PARALLEL CORPUS CONSTRUCTION METHOD, AND INFORMATION PROCESSING APPARATUS FUJITSU LIMITED (JP) 2024-07-03 EP disclosed
US-11905530-B2 Cell encapsulation device comprising a pancreatic progenitor cell population VIACYTE, INC. (US) 2024-02-20 US disclosed
US-11896622-B2 Methods of producing pancreatic hormones VIACYTE, INC. (US) 2024-02-13 US disclosed
US-20230285296-A1 LAYER-BY-LAYER COATED NANOLIPOSOME FOR ORAL DELIVERY OF INSULIN NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2023-09-14 US disclosed
CN-1287166-A Separation, extracorporeal culture, preparation and application of human primitive mesenchymal stem cell population HE QINGHUA (CN) 2001-03-14 CN disclosed
CN-1206420-A Novel A1 adenosine receptor agonists and antagonists UNIV FLORIDA (US) 1999-01-27 CN disclosed
CN-1182432-A Human neuropeptide receptor HUMAN GENOME SCIENCES INC (US) 1998-05-20 CN disclosed
US-5480999-A CONTAINING AN ACID AND AN ARGININE ANALOGUE SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1996-01-02 US disclosed
US-5360925-A Cardio cerebrovascular disorders, antiinflammatory agents and immune disorders SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) 1994-11-01 US disclosed
EP-0116938-A1 Benzoheterocyclic carbamates USV PHARMACEUTICAL CORPORATION (US) 1984-08-29 EP disclosed
US-4456687-A CULTURES; CYCLIC ADENOSINE-3'-PHOSPHATE STIMULANTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1984-06-26 US disclosed