Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427158 | 0.83 | DRD2 (0.34) | MPOKRASJAK2JAK3PTK2 | |
| SCHEMBL8884101 | 0.83 | JAK2 (0.34) | MPOKRASJAK2JAK3PTK2 | |
| SCHEMBL8883615 | 0.83 | KRAS (0.34) | MPOKRASJAK2JAK3PTK2 | |
| SCHEMBL8884423 | 0.80 | FFAR4 (0.34) | MPOKRASJAK2JAK3PTK2 | |
| SCHEMBL8886319 | 0.80 | KRAS (0.33) | MPOKRASJAK2JAK3PTK2 | |
| SCHEMBL8885657 | 0.79 | CA1 (0.33) | MPOKRASJAK2JAK3PTK2 | |
| SCHEMBL8885917 | 0.78 | MPO (0.35) | MPOKRASJAK2JAK3PTK2 | |
| SCHEMBL8885913 | 0.78 | FFAR4 (0.35) | MPOKRASJAK2JAK3PTK2 | |
| SCHEMBL8884979 | 0.77 | KRAS (0.32) | MPOKRAS | |
| SCHEMBL12922484 | 0.73 | CYP2D6 (0.49) | MPOKRASJAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663119-A | FOR USE IN AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1997-09-02 | — | — | US | disclosed |
| US-5523280-A | TREATING PLANT DISEASES | RHONE-POULENC AGROCHIMIE (FR) | 1996-06-04 | — | — | US | disclosed |
| EP-0538156-A1 | Fungicidal phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1993-04-21 | — | — | EP | disclosed |