Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884101 | 0.79 | JAK2 (0.34) | KRASFFAR4MPOJAK2JAK3 | |
| SCHEMBL8427158 | 0.79 | DRD2 (0.34) | KRASFFAR4MPOJAK2JAK3 | |
| SCHEMBL8883615 | 0.79 | KRAS (0.34) | KRASFFAR4MPOJAK2JAK3 | |
| SCHEMBL8884423 | 0.79 | FFAR4 (0.34) | KRASFFAR4MPOJAK2JAK3 | |
| SCHEMBL8885913 | 0.77 | FFAR4 (0.35) | KRASFFAR4MPOJAK2JAK3 | |
| SCHEMBL8975989 | 0.76 | TDP1 (0.42) | CA1CA2CA7CA9S100A4 | |
| SCHEMBL8886319 | 0.76 | KRAS (0.33) | KRASFFAR4MPOJAK2JAK3 | |
| SCHEMBL8429227 | 0.75 | TDP1 (0.31) | — | |
| SCHEMBL8885917 | 0.74 | MPO (0.35) | KRASMPOJAK2JAK3PTK2 | |
| SCHEMBL18253155 | 0.73 | MAPT (0.36) | KRASFFAR4JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663119-A | FOR USE IN AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1997-09-02 | — | — | US | disclosed |
| US-5523280-A | TREATING PLANT DISEASES | RHONE-POULENC AGROCHIMIE (FR) | 1996-06-04 | — | — | US | disclosed |
| EP-0538156-A1 | Fungicidal phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1993-04-21 | — | — | EP | disclosed |