Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884353 | 0.90 | WHR1 (0.49) | WHR1L3MBTL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL8885954 | 0.79 | WHR1 (0.50) | WHR1L3MBTL1ACACAABCG2SMN1; SMN2 | |
| SCHEMBL7819852 | 0.79 | WHR1 (0.48) | WHR1L3MBTL1PIK3CDPIK3CAPIK3CB | |
| Hydrochloric Acid SCHEMBL8131298 | 0.78 | WHR1 (0.49) | WHR1L3MBTL1PIK3CDPIK3CAPIK3CB | |
| Hydrochloric Acid SCHEMBL8139103 | 0.77 | WHR1 (0.46) | WHR1L3MBTL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL7825968 | 0.77 | WHR1 (0.46) | WHR1L3MBTL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL7820197 | 0.77 | PDE4A (0.48) | WHR1L3MBTL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL8138601 | 0.75 | WHR1 (0.42) | WHR1L3MBTL1PDE4APDE4BPDE4D | |
| SCHEMBL8884921 | 0.75 | KDM4E (0.48) | WHR1L3MBTL1PDE4APDE4DKDM4E | |
| SCHEMBL27767946 | 0.74 | L3MBTL1 (0.58) | L3MBTL1ACACAPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650410-A | ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-22 | — | — | US | disclosed |