Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884921 | 0.82 | KDM4E (0.48) | WHR1L3MBTL1ABCG2PDGFRBPDGFRA | |
| SCHEMBL8886069 | 0.81 | WHR1 (0.43) | WHR1L3MBTL1ABCG2PDGFRBPDGFRA | |
| SCHEMBL8885068 | 0.79 | WHR1 (0.50) | WHR1L3MBTL1ABCG2ACACASMN1; SMN2 | |
| SCHEMBL7819852 | 0.79 | WHR1 (0.48) | WHR1L3MBTL1ABCG2PDGFRBPDGFRA | |
| Diphenylamine SCHEMBL8885083 | 0.79 | ABCG2 (0.55) | WHR1L3MBTL1ABCG2ABCB1ABCC1 | |
| SCHEMBL8884725 | 0.78 | WHR1 (0.41) | WHR1L3MBTL1PDGFRBPDGFRAMAPT | |
| SCHEMBL8884353 | 0.78 | WHR1 (0.49) | WHR1L3MBTL1PDGFRBPDGFRAACACA | |
| Hydrochloric Acid SCHEMBL8131298 | 0.78 | WHR1 (0.49) | WHR1L3MBTL1ABCG2ACACASMN1; SMN2 | |
| SCHEMBL7825968 | 0.77 | WHR1 (0.46) | WHR1L3MBTL1PDGFRBPDGFRAACACA | |
| SCHEMBL7820197 | 0.77 | PDE4A (0.48) | WHR1L3MBTL1PDGFRBPDGFRAACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650410-A | ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-22 | — | — | US | disclosed |