Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ACACA | Q13085 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326797 | 0.75 | ABCG2 (0.57) | L3MBTL1ACACAABCG2ABCB1ABCC1 | |
| SCHEMBL8885068 | 0.74 | WHR1 (0.50) | L3MBTL1ACACANPC1KDM4EALDH1A1 | |
| SCHEMBL8885954 | 0.74 | WHR1 (0.50) | L3MBTL1ACACAABCG2ABCB1ABCC1 | |
| SCHEMBL15075259 | 0.74 | L3MBTL1 (1.00) | L3MBTL1ACACANPC1KDM4EALDH1A1 | |
| SCHEMBL6001414 | 0.73 | ABCG2 (0.58) | L3MBTL1ACACAABCG2ABCB1ABCC1 | |
| Hydrochloric Acid SCHEMBL8131298 | 0.73 | WHR1 (0.49) | L3MBTL1ACACANPC1KDM4EALDH1A1 | |
| SCHEMBL8884353 | 0.73 | WHR1 (0.49) | L3MBTL1ACACANPC1KDM4EALDH1A1 | |
| SCHEMBL7819852 | 0.73 | WHR1 (0.48) | L3MBTL1ACACANPC1KDM4EALDH1A1 | |
| SCHEMBL8818335 | 0.73 | L3MBTL1 (0.53) | L3MBTL1ACACANPC1KDM4EALDH1A1 | |
| SCHEMBL7820197 | 0.71 | PDE4A (0.48) | L3MBTL1ACACAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490016-A | 2,4-substituted quinazolines as lipid kinase inhibitors | NOVARTIS AG (CH) | 2009-07-22 | — | — | CN | claimed |
| CN-101490016-A | 2,4-substituted quinazolines as lipid kinase inhibitors | NOVARTIS AG (CH) | 2009-07-22 | — | — | CN | disclosed |