SCHEMBL888525

SCHEMBL888525

CCOC(=O)C(C)C1C2CC3CC(C2)CC1(OCC(C)C)C3

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
EPHX2 P34913 2/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 6/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
PRKCA P17252 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888634 0.90 LMNA (0.39) LMNAEPHX2CYP3A4CYP2D6CYP2C9
SCHEMBL27842119 0.86 EPHX2 (0.33) LMNAEPHX2
SCHEMBL888549 0.85 LMNA (0.39) LMNAEPHX2CYP3A4CYP2D6CYP2C9
SCHEMBL888451 0.82 ALDH1A1 (0.40) LMNAALDH1A1MEN1KMT2ATSHR
SCHEMBL28524737 0.79 SMN1; SMN2 (0.36) LMNAEPHX2ALDH1A1MEN1KMT2A
SCHEMBL888522 0.77 EPHX2 (0.39) LMNAEPHX2CYP3A4CYP2D6CYP2C9
SCHEMBL27924523 0.74 ALDH1A1 (0.33) LMNAEPHX2ALDH1A1KMT2A
SCHEMBL888274 0.73 ALDH1A1 (0.38) LMNAEPHX2ALDH1A1KMT2A
SCHEMBL819750 0.70 EPHX2 (0.34) EPHX2
SCHEMBL6860739 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
CN-103044584-A Method for preparing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL CO 2013-04-17 CN disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed