SCHEMBL888451

SCHEMBL888451

CCOC12CC3CC(CC(C3)C1C(C)C(=O)OC)C2

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
LMNA P02545 1/20 0.38
ITGB1 P05556 1/20 0.34
ITGA4 P13612 1/20 0.34
KMT2A Q03164 5/20 0.34
MEN1 O00255 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888634 0.92 LMNA (0.39) ALDH1A1LMNAKMT2AMEN1SMN1; SMN2
SCHEMBL28524737 0.86 SMN1; SMN2 (0.36) ALDH1A1LMNAITGB1ITGA4KMT2A
SCHEMBL888274 0.85 ALDH1A1 (0.38) ALDH1A1LMNAITGB1ITGA4KMT2A
SCHEMBL888549 0.83 LMNA (0.39) ALDH1A1LMNAKMT2AMEN1TSHR
SCHEMBL888525 0.82 LMNA (0.37) ALDH1A1LMNAKMT2AMEN1TSHR
SCHEMBL27842119 0.73 EPHX2 (0.33) LMNASMN1; SMN2
SCHEMBL5607981 0.70 LMNA (0.36) ALDH1A1LMNAKMT2AMEN1SMN1; SMN2
SCHEMBL888448 0.69 EPHX2 (0.40) ALDH1A1LMNATSHR
SCHEMBL2741163 0.68 ALDH1A1 (0.36) ALDH1A1LMNAKMT2AMEN1SMN1; SMN2
SCHEMBL888631 0.67 EPHX2 (0.42) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed