Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.59 |
| ▸ | AGT | P01019 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885235 | 0.90 | AGTR1 (0.54) | AGTR1AGTR2AGT | |
| SCHEMBL8886621 | 0.83 | AGTR1 (0.56) | AGTR1AGTR2AGT | |
| SCHEMBL595068 | 0.80 | AGTR1 (0.56) | AGTR1AGTR2AGT | |
| SCHEMBL9402017 | 0.80 | AGTR1 (0.69) | AGTR1AGTR2AGT | |
| SCHEMBL2070872 | 0.80 | AGTR2 (0.57) | AGTR1AGTR2AGT | |
| SCHEMBL9030074 | 0.79 | AGTR1 (0.65) | AGTR1AGTR2AGT | |
| SCHEMBL8884915 | 0.79 | AGTR1 (0.56) | AGTR1AGTR2AGT | |
| SCHEMBL7304474 | 0.79 | AGTR1 (0.64) | AGTR1AGTR2AGT | |
| SCHEMBL9030137 | 0.79 | AGTR2 (0.64) | AGTR1AGTR2AGT | |
| SCHEMBL14855527 | 0.78 | AGTR1 (0.66) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599823-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| US-5356911-A | Hypotensive agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| EP-0542059-A1 | Substituted biphenylpyridinones as angiotensin II antagonists | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |