Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883122 | 0.91 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19GAACYP2C9 | |
| SCHEMBL9208140 | 0.91 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C19GAACYP2C9 | |
| SCHEMBL9211024 | 0.80 | MEN1 (0.41) | CYP1A2CYP3A4CYP2C19GAACYP2C9 | |
| SCHEMBL9212851 | 0.78 | POLB (0.41) | GAATSHRHDAC6NPSR1MAPT | |
| SCHEMBL9199484 | 0.78 | TSHR (0.44) | CYP1A2CYP3A4CYP2C19GAACYP2C9 | |
| SCHEMBL9396759 | 0.78 | PDE4D (0.41) | CYP1A2CYP3A4CYP2C19GAACYP2C9 | |
| SCHEMBL9275055 | 0.78 | HDAC6 (0.38) | CYP1A2CYP3A4CYP2C19GAACYP2C9 | |
| SCHEMBL9272528 | 0.78 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C19GAACYP2C9 | |
| SCHEMBL9278089 | 0.77 | PTAFR (0.42) | CYP1A2CYP3A4CYP2C19GAACYP2C9 | |
| SCHEMBL9213233 | 0.77 | LMNA (0.43) | MAPTPOLBTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652363-A | TREATING PLATELET ACTIVATING FACTOR MEDIATED DISEASES | C.D. SEARLE & CO. (US) | 1997-07-29 | — | — | US | disclosed |