Trolamine

Trolamine

SCHEMBL8885448

CNCC(O)CO.OCCN(CCO)CCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
THRB P10828 1/20 0.33
KISS1R Q969F8 2/20 0.32
CARM1 Q86X55 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL8530734 0.88 LMNA (0.33) KDM4EALDH1A1LMNA
SCHEMBL4868603 0.83
SCHEMBL1868586 0.83
SCHEMBL337338 0.83
Hydrochloric Acid SCHEMBL3193718 0.81
Trolamine SCHEMBL6524533 0.78 LMNA (0.56) KDM4EALDH1A1LMNATHRB
Meglumine SCHEMBL22352698 0.78 KDM4E (0.73) KDM4ELMNA
SCHEMBL8885445 0.77 KDM4E (0.43) KDM4EALDH1A1LMNATHRBKISS1R
SCHEMBL22562879 0.77 KDM4E (0.46) KDM4EALDH1A1LMNATHRBKISS1R
Trolamine SCHEMBL28100199 0.76 LMNA (0.53) KDM4EALDH1A1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631389-A SUCCINAMIDES WITH SUGAR GROUPS, POLLUTION CONTROL, BIODEGRADABLE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-05-20 US disclosed
US-5541341-A CARBOHYDRATE BASED SURFACTANTS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-07-30 US disclosed