Trolamine

Trolamine

SCHEMBL6524533

OCC(O)CO.OCCN(CCO)CCO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
ALDH1A1 P00352 2/20 0.56
THRB P10828 1/20 0.45
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.33
TSHR P16473 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PNP P00491 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
P2RX3 P56373 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL28274608 0.97 LMNA (0.53) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL28100199 0.97 LMNA (0.53) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL28109599 0.92 LMNA (0.47) LMNAALDH1A1THRBKDM4ETSHR
Trolamine SCHEMBL27661615 0.89 TDP1 (0.50) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL9616233 0.87 LMNA (0.43) LMNAALDH1A1THRBKDM4EMAPT
Trolamine SCHEMBL27439255 0.85 ALDH1A1 (0.41) LMNAALDH1A1THRBKDM4EMAPT
Glycerin SCHEMBL5691791 0.83 LMNA (0.39) LMNAALDH1A1THRBKDM4ETSHR
Trolamine SCHEMBL29008328 0.83 MAPT (0.39) THRBKDM4EMAPTTSHRALOX15
SCHEMBL3279037 0.82 KDM4E (0.47) LMNAALDH1A1THRBKDM4EMAPT
SCHEMBL32670384 0.80 KDM4E (0.46) LMNAALDH1A1THRBKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115453043-A Long-acting stable liquid calcium indicator 深圳市考拉生态科技有限公司 2022-12-09 CN claimed
CN-115166137-A Method for detecting various calcium-containing compounds in absorption liquid after smoke absorption 深圳市考拉生态科技有限公司 2022-10-11 CN claimed
CN-113262189-A Tightening and wrinkle-reducing eye cream 广东美集科技有限公司 2021-08-17 CN claimed
US-20190004477-A1 OPTICAL DEVICES FOR AUTHENTICATION AND METHODS OF MAKING SAME TECHNOLOGICAL UNIVERSITY DUBLIN (IE) 2019-01-03 US claimed
EP-3394680-A1 OPTICAL DEVICES FOR AUTHENTICATION AND METHODS OF MAKING SAME Dublin Institute of Technology (IE) 2018-10-31 EP claimed
CN-107998340-A A kind of Weight-reducing health cream and preparation method thereof 蒋卫东 2018-05-08 CN claimed
CN-107118863-A A kind of modified high molecular nanometer glass cleaner 江苏天恒纳米科技股份有限公司 2017-09-01 CN claimed
JP-8302009-A None JP disclosed
CN-115453043-A Long-acting stable liquid calcium indicator 深圳市考拉生态科技有限公司 2022-12-09 CN disclosed
CN-115453043-A Long-acting stable liquid calcium indicator 深圳市考拉生态科技有限公司 2022-12-09 CN disclosed
CN-115166137-A Method for detecting various calcium-containing compounds in absorption liquid after smoke absorption 深圳市考拉生态科技有限公司 2022-10-11 CN disclosed
CN-217090760-U Wearable and deformable muscle bone sound guide pad 中国人民解放军总医院海南医院 2022-08-02 CN disclosed
CN-113262189-A Tightening and wrinkle-reducing eye cream 广东美集科技有限公司 2021-08-17 CN disclosed
US-5290894-A Acrolein polymers modified with tetrahydrofuran for aldol-Michael condensation for microbiocides BIOPOLYMERS LIMITED (AU) 1994-03-01 US disclosed
CN-1063413-A PAIN RELIEVING MESSAGE EMULSION WANG CHUNRONG (CN) 1992-08-12 CN disclosed
US-5041234-A Transparent soap bars which may contain short chain monohydric alcohols, and a method of making the same LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1991-08-20 US disclosed
EP-0339044-A4 BIOSTATIC AND BIOCIDAL COMPOSITIONS. BIOPOLYMERS LTD (AU) 1990-05-14 EP disclosed
EP-0339044-A1 BIOSTATIC AND BIOCIDAL COMPOSITIONS. BIOPOLYMERS LTD (AU) 1989-11-02 EP disclosed
EP-0335640-A2 Transparent soap bars UNILEVER PLC (GB) 1989-10-04 EP disclosed
WO-1988004671-A1 BIOSTATIC AND BIOCIDAL COMPOSITIONS BIOPOLYMERS LIMITED (AU) 1988-06-30 WO disclosed