Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.55 |
| ▸ | PDE4A | P27815 | 3/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.54 |
| ▸ | WHR1 | P49842 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.48 |
| ▸ | KRAS | P01116 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL8136070 | 0.82 | PDE4A (0.56) | ABCG2PDE4APDE4DWHR1L3MBTL1 | |
| SCHEMBL12069892 | 0.79 | FBP1 (0.74) | ABCG2FBP1EGFRKRASSOS1 | |
| SCHEMBL8885954 | 0.79 | WHR1 (0.50) | ABCG2WHR1L3MBTL1ABCB1ABCC1 | |
| SCHEMBL13296171 | 0.77 | PDE4A (0.67) | PDE4APDE4DWHR1EGFRSMN1; SMN2 | |
| SCHEMBL14438925 | 0.74 | MAPK14 (0.59) | PDE4APDE4DWHR1EGFRTP53 | |
| SCHEMBL3472098 | 0.73 | PDE4A (0.62) | PDE4APDE4DWHR1FBP1EGFR | |
| Hydrochloric Acid SCHEMBL8492560 | 0.72 | WHR1 (0.51) | ABCG2PDE4APDE4DWHR1L3MBTL1 | |
| SCHEMBL16404474 | 0.72 | ABCG2 (0.74) | ABCG2WHR1ABCB1EGFRABCC1 | |
| SCHEMBL8492556 | 0.71 | L3MBTL1 (0.50) | ABCG2PDE4APDE4DWHR1L3MBTL1 | |
| SCHEMBL8885068 | 0.71 | WHR1 (0.50) | ABCG2PDE4APDE4DWHR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650410-A | ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-22 | — | — | US | disclosed |