SCHEMBL888605

SCHEMBL888605

CCOC(=O)C(COCC(C)C)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.34
TSHR P16473 4/20 0.33
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31
METAP2 P50579 1/20 0.31
METAP1 P53582 1/20 0.31
CTSK P43235 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
CPB2 Q96IY4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820522 0.86 ALDH1A1 (0.37) MMP8TSHRALDH1A1HSD17B10LMNA
SCHEMBL888588 0.86 MMP8 (0.36) MMP8L3MBTL1TSHRALDH1A1HSD17B10
SCHEMBL20995942 0.81 HSD17B10 (0.41) MMP8TSHRALDH1A1HSD17B10LMNA
SCHEMBL819040 0.79 ALDH1A1 (0.37) MMP8TSHRALDH1A1HSD17B10LMNA
SCHEMBL13537881 0.79 MMP8 (0.41) MMP8ALDH1A1HSD17B10LMNAALOX15
SCHEMBL819840 0.77 L3MBTL1 (0.33) L3MBTL1TSHR
SCHEMBL888252 0.77 ALDH1A1 (0.36) MMP8L3MBTL1TSHRALDH1A1HSD17B10
SCHEMBL17617125 0.76 ALDH1A1 (0.42) MMP8TSHRALDH1A1HSD17B10LMNA
SCHEMBL17617142 0.76 ALDH1A1 (0.42) MMP8TSHRALDH1A1HSD17B10LMNA
SCHEMBL17617121 0.76 ALDH1A1 (0.42) MMP8TSHRALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130190464-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-25 US disclosed
US-20130109789-A1 OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-02 US disclosed
CN-103044584-A Method for preparing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL CO 2013-04-17 CN disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed