Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 15/20 | 1.00 |
| ▸ | HTR1B | P28222 | 13/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886184 | 0.82 | HTR1D (1.00) | HTR1DHTR1BHTR1A | |
| SCHEMBL13533349 | 0.79 | HTR1D (1.00) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL8316476 | 0.79 | HTR1D (1.00) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL8886408 | 0.76 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8124390 | 0.73 | HTR1D (0.83) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL8784460 | 0.69 | HTR1A (0.67) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL11267287 | 0.69 | HTR1A (0.64) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL8887147 | 0.67 | HTR1D (0.54) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL9186743 | 0.67 | DRD2 (0.80) | HTR1DHTR1BHTR1ADRD2 | |
| SCHEMBL13534482 | 0.65 | HTR1D (0.77) | HTR1DHTR1BHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650427-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1997-07-22 | — | — | US | disclosed |
| US-5461061-A | Antidepressants | WIKSTROM HAKAN V (NL) | 1995-10-24 | — | — | US | disclosed |
| US-5288748-A | Antidepressants | THE UPJOHN COMPANY (US) | 1994-02-22 | — | — | US | disclosed |