SCHEMBL8887405

SCHEMBL8887405

CCOC(=O)CC1CCCCC1C(=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
MEN1 O00255 1/20 0.36
CYP2D6 P10635 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
PPM1B O75688 1/20 0.36
PTPN1 P18031 1/20 0.36
PPP1CC P36873 1/20 0.36
TRPA1 O75762 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29248863 0.90 GAA (0.39) ALDH1A1KMT2APOLBMGAMGAA
SCHEMBL4769429 0.86 ALDH1A1 (0.42) ALDH1A1KMT2APOLBMGAMGAA
SCHEMBL8960286 0.86 ALDH1A1 (0.40) ALDH1A1KMT2ATP53CYP3A4MEN1
SCHEMBL15653541 0.85 MGAM (0.46) ALDH1A1KMT2APOLBMGAMGAA
SCHEMBL2295020 0.84 TP53 (0.46) ALDH1A1KMT2ATP53CYP3A4MEN1
SCHEMBL763361 0.84 TP53 (0.46) ALDH1A1KMT2ATP53CYP3A4MEN1
SCHEMBL10289783 0.84 TP53 (0.46) ALDH1A1KMT2ATP53CYP3A4MEN1
SCHEMBL13616930 0.82 ALDH1A1 (0.45) ALDH1A1KMT2ATP53CYP3A4MEN1
SCHEMBL4617750 0.82 ALDH1A1 (0.41) ALDH1A1KMT2ATP53CYP3A4MEN1
SCHEMBL6900183 0.81 TP53 (0.53) ALDH1A1KMT2ATP53CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5614486-A DIETHYL 1,4-CYCLOHEXANEDICARBOXYLATE FIRMENICH SA (CH) 1997-03-25 US disclosed