SCHEMBL8960286

SCHEMBL8960286

CCOC(=O)C1CCCCC1CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
PPM1B O75688 1/20 0.39
PTPN1 P18031 1/20 0.39
PPP1CC P36873 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 2/20 0.37
PKM P14618 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8887405 0.86 ALDH1A1 (0.40) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL10289783 0.84 TP53 (0.46) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL2295020 0.84 TP53 (0.46) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL763361 0.84 TP53 (0.46) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL4617750 0.82 ALDH1A1 (0.41) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL8960544 0.82 SLC6A2 (0.41) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL13616930 0.82 ALDH1A1 (0.45) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL13011542 0.81 TP53 (0.53) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL6900183 0.81 TP53 (0.53) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL234644 0.81 TP53 (0.53) ALDH1A1PPM1BPTPN1PPP1CCTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694605-A2 Cyclic diesters and their use as perfuming ingredients FIRMENICH SA (CH) 1996-01-31 EP disclosed