Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677351 | 0.81 | ENPP2 (0.49) | ENPP2TDP1PHLPP2LMNAMAPT | |
| SCHEMBL10394559 | 0.80 | ENPP2 (0.48) | ENPP2TDP1PHLPP2LMNACA1 | |
| SCHEMBL28977413 | 0.78 | MAPT (0.51) | TDP1LMNASMN1; SMN2MAPTPKM | |
| SCHEMBL30360235 | 0.78 | MAPT (0.51) | TDP1LMNASMN1; SMN2MAPTPKM | |
| SCHEMBL10482234 | 0.76 | ALDH1A1 (0.42) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL66550 | 0.75 | ENPP2 (0.60) | ENPP2TDP1CDK1PHLPP2SMN1; SMN2 | |
| SCHEMBL1755227 | 0.75 | ENPP2 (0.56) | ENPP2TDP1CDK1PHLPP2SMN1; SMN2 | |
| SCHEMBL11655370 | 0.75 | CASR (0.34) | ENPP2LMNASMN1; SMN2PKMKMT2A | |
| SCHEMBL11289339 | 0.74 | ALDH1A1 (0.41) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9358421 | 0.74 | ALDH1A1 (0.45) | ENPP2TDP1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654410-A | LIGHTFASTNESS, OXIDATION RESISTANCE | CLARIANT FINANCE (BVI) LIMITED (VG) | 1997-08-05 | — | — | US | disclosed |
| US-5386015-A | Fiber-reactive dyes | SANDOZ LTD. (CH) | 1995-01-31 | — | — | US | disclosed |
| EP-0365486-A2 | Fibre-reactive azo dyes | SANDOZ AG (CH) | 1990-04-25 | — | — | EP | disclosed |
| US-4128544-A | DYES FOR NATURAL OR REGENERATED CELLULOSE | SANDOZ LTD. (CH) | 1978-12-05 | — | — | US | disclosed |