Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889750 | 0.88 | GAA (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8889422 | 0.84 | TTK (0.52) | RXRARXRBDHODHMAPTALDH1A1 | |
| SCHEMBL8887610 | 0.81 | PTDSS1 (0.38) | DHODHMAPTALDH1A1LMNAADORA2A | |
| SCHEMBL8889311 | 0.81 | HSP90AA1 (0.41) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8889764 | 0.81 | SMN1; SMN2 (0.51) | TSHRKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8887278 | 0.81 | GABRA1 (0.46) | RXRARXRBGABRA1GABRG2GABRB3 | |
| SCHEMBL8889929 | 0.81 | MAPK13 (0.44) | ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL8887907 | 0.81 | SMN1; SMN2 (0.46) | RXRARXRBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17279847 | 0.80 | CCNE2 (0.45) | TSHRMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8889925 | 0.80 | MAP2K4 (0.45) | ALDH1A1ADORA3ADORA2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |