Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740414 | 0.78 | PNMT (0.41) | HTR2AHTR2CHTR2BHRH3CHRNB2 | |
| SCHEMBL908349 | 0.78 | DRD2 (0.38) | DRD2HTR2AMLNRADRB2ADRB1 | |
| SCHEMBL15724653 | 0.77 | TDP1 (0.56) | DRD2HTR2AMLNRADRB2ADRB1 | |
| SCHEMBL15749929 | 0.77 | TDP1 (0.56) | DRD2HTR2AMLNRADRB2ADRB1 | |
| SCHEMBL19894308 | 0.75 | DRD2 (0.35) | DRD2HTR2AACHE | |
| SCHEMBL17193927 | 0.73 | AKR1B1 (0.46) | DRD2HTR2AMLNRADRB2ADRB1 | |
| SCHEMBL4225298 | 0.73 | HRH3 (0.40) | DRD2HTR2AMLNRADRB2ADRB1 | |
| SCHEMBL18469563 | 0.73 | AKR1B1 (0.45) | DRD2HTR2AMLNRADRB2ADRB1 | |
| SCHEMBL20665136 | 0.73 | HTR2A (0.47) | DRD2HTR2AMLNRADRB2ADRB1 | |
| SCHEMBL4225302 | 0.73 | HRH3 (0.40) | DRD2HTR2AMLNRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |