Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | TPMT | P51580 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095930 | 0.96 | PKM (0.46) | MEN1KMT2APOLBL3MBTL1PKM | |
| SCHEMBL20010428 | 0.81 | PKM (0.36) | MEN1KMT2APOLBL3MBTL1PKM | |
| Water SCHEMBL8887299 | 0.80 | AKR1C3 (0.51) | MEN1KMT2APOLBL3MBTL1PKM | |
| SCHEMBL2346165 | 0.80 | AKR1C3 (0.51) | MEN1KMT2APOLBL3MBTL1PKM | |
| SCHEMBL7287581 | 0.78 | TSHR (0.52) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL9726925 | 0.76 | PKM (0.47) | MEN1KMT2APOLBL3MBTL1PKM | |
| SCHEMBL11737816 | 0.71 | KDM5A (0.48) | MEN1KMT2APOLBL3MBTL1PKM | |
| SCHEMBL10665479 | 0.71 | AKR1C3 (0.35) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL2884556 | 0.70 | KDM4E (0.61) | MEN1KMT2APOLBL3MBTL1PKM | |
| SCHEMBL999842 | 0.70 | CYP1A2 (0.47) | MEN1KMT2APOLBL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |