Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15390559 | 0.98 | CYP1A2 (0.45) | CYP1A2MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL136658 | 0.95 | CYP1A2 (0.52) | CYP1A2MEN1KMT2APOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL28348867 | 0.93 | CYP1A2 (0.50) | CYP1A2MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL15995224 | 0.85 | POLB (0.47) | CYP1A2MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL27606752 | 0.85 | AKR1C3 (0.50) | CYP1A2MEN1KMT2APOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL15995512 | 0.83 | POLB (0.46) | CYP1A2MEN1KMT2APOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL15995197 | 0.83 | POLB (0.46) | CYP1A2MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL29766665 | 0.78 | AKR1C3 (0.56) | MEN1KMT2AL3MBTL1PKMCA12 | |
| SCHEMBL133823 | 0.78 | AKR1C3 (0.56) | MEN1KMT2AL3MBTL1PKMCA12 | |
| SCHEMBL3654278 | 0.76 | P2RY14 (0.61) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315864-B2 | Heteroarylcyanine dyes with sulfonic acid substituents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315864-B2 | Heteroarylcyanine dyes with sulfonic acid substituents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20140080127-A1 | HETEROARYLCYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-7868135-B2 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | BIOWEST THERAPEUTICS INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| EP-2147925-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2010-01-27 | — | — | EP | disclosed |
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-17 | — | — | US | disclosed |
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-25 | — | — | US | disclosed |
| EP-1656390-A2 | COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF | MIGENIX INC. (CA) | 2006-05-17 | — | — | EP | disclosed |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2005-07-14 | — | — | US | disclosed |
| WO-2005000878-A2 | COMPOSITIONS OF LIPOPEPTIDE ANTIBIOTIC DERIVATIVES AND METHODS OF USE THEREOF | MIGENIX INC. (CA) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | HAVCR2, ADAR, NSUN2 | CYP1A2 3094/4885MEN1 4687/4885KMT2A 3406/4885 |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | NRDC, NOD2, NGLY1 | CYP1A2 4441/4885MEN1 3085/4885KMT2A 4429/4885 |
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | POLQ, POLI, POLH | CYP1A2 4344/4885MEN1 3230/4885KMT2A 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.