Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22621594 | 0.78 | RXRA (0.50) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL8889564 | 0.78 | MRGPRX4 (0.39) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL8889567 | 0.78 | MRGPRX4 (0.39) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL12967974 | 0.75 | MRGPRX4 (0.44) | IDO1MRGPRX4PPARGRXRARXRB | |
| SCHEMBL12968476 | 0.74 | MRGPRX4 (0.43) | IDO1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL12968030 | 0.74 | MRGPRX4 (0.43) | IDO1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL24305899 | 0.72 | MRGPRX4 (0.47) | IDO1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL13347573 | 0.72 | NR3C2 (0.49) | IDO1NR3C2NR3C1 | |
| SCHEMBL12958346 | 0.72 | MRGPRX4 (0.41) | IDO1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL15473206 | 0.71 | XDH (0.47) | IDO1MRGPRX4DRD2AAK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |