Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887789 | 0.78 | IDO1 (0.44) | MRGPRX4PPARGIDO1RXRARXRB | |
| SCHEMBL8889567 | 0.77 | MRGPRX4 (0.39) | MRGPRX4PPARGIDO1RXRARXRB | |
| SCHEMBL22621594 | 0.75 | RXRA (0.50) | MRGPRX4PPARGIDO1RXRARXRB | |
| SCHEMBL5665054 | 0.72 | CA1 (0.36) | — | |
| SCHEMBL12967974 | 0.72 | MRGPRX4 (0.44) | MRGPRX4PPARGIDO1RXRARXRB | |
| SCHEMBL8889730 | 0.72 | ALDH1A1 (0.40) | PPARG | |
| SCHEMBL12968476 | 0.71 | MRGPRX4 (0.43) | MRGPRX4IDO1RXRARXRBRXRG | |
| SCHEMBL12968030 | 0.71 | MRGPRX4 (0.43) | MRGPRX4IDO1RXRARXRBRXRG | |
| SCHEMBL5143774 | 0.70 | MAPK1 (0.49) | PPARGRXRA | |
| SCHEMBL24305899 | 0.69 | MRGPRX4 (0.47) | MRGPRX4IDO1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |