Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.87 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.87 |
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | BCHE | P06276 | 4/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254006 | 1.00 | LTA4H (0.87) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL10405807 | 1.00 | LTA4H (0.87) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL7367359 | 1.00 | LTA4H (0.87) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL5760428 | 0.98 | LTA4H (0.90) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL1563277 | 0.93 | LTA4H (1.00) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL11687518 | 0.92 | LTA4H (0.97) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL12040562 | 0.91 | LTA4H (0.77) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL12630258 | 0.91 | LTA4H (0.77) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL14300868 | 0.89 | LTA4H (0.90) | LTA4HEPHX2MGLLBCHEFFAR1 | |
| SCHEMBL16705571 | 0.86 | LTA4H (0.70) | LTA4HEPHX2MGLLLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |