Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16705571 | 1.00 | LTA4H (0.70) | LTA4HEPHX2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10438662 | 0.98 | LTA4H (0.72) | LTA4HEPHX2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7433717 | 0.93 | LTA4H (0.74) | LTA4HEPHX2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7036584 | 0.91 | MGLL (0.67) | LTA4HEPHX2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9453126 | 0.88 | CYP4F2 (0.64) | LTA4HEPHX2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9451327 | 0.87 | ALDH1A1 (0.69) | LTA4HEPHX2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7367359 | 0.86 | LTA4H (0.87) | LTA4HEPHX2LMNACYP1A2PTGS1 | |
| SCHEMBL8888466 | 0.86 | LTA4H (0.87) | LTA4HEPHX2LMNACYP1A2PTGS1 | |
| SCHEMBL10405807 | 0.86 | LTA4H (0.87) | LTA4HEPHX2LMNACYP1A2PTGS1 | |
| SCHEMBL9254006 | 0.86 | LTA4H (0.87) | LTA4HEPHX2LMNACYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939173-A | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-03 | — | — | US | claimed |
| EP-0373587-A2 | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-20 | — | — | EP | claimed |
| CN-115304502-B | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-10-18 | — | — | CN | disclosed |
| CN-115304502-A | FOXM1 inhibitor and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-08 | — | — | CN | disclosed |
| US-5177108-A | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-01-05 | — | — | US | disclosed |
| US-5077315-A | Treatment of HIV virus | MERRELL DOW PHARMACEUTICALS (US) | 1991-12-31 | — | — | US | disclosed |
| US-4939173-A | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0373587-A2 | Aryloxy alkanols as anti-retrovirus agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-20 | — | — | EP | disclosed |