SCHEMBL5760428

SCHEMBL5760428

OCCCCc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.90

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.90
EPHX2 P34913 1/20 0.90
BCHE P06276 4/20 0.63
FFAR1 O14842 1/20 0.61
FFAR4 Q5NUL3 1/20 0.61
MGLL Q99685 2/20 0.60
LMNA P02545 1/20 0.59
CYP1A2 P05177 1/20 0.59
PTGS1 P23219 1/20 0.59
SLC6A2 P23975 1/20 0.59
CYP2C19 P33261 1/20 0.59
PTGS2 P35354 1/20 0.59
SLC6A3 Q01959 1/20 0.59
HIF1A Q16665 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
ALOX5 P09917 1/20 0.56
MAOB P27338 1/20 0.54
CYP4F2 P78329 1/20 0.54
CYP4A11 Q02928 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9254006 0.98 LTA4H (0.87) LTA4HEPHX2BCHEFFAR1FFAR4
SCHEMBL10405807 0.98 LTA4H (0.87) LTA4HEPHX2BCHEFFAR1FFAR4
SCHEMBL7367359 0.98 LTA4H (0.87) LTA4HEPHX2BCHEFFAR1FFAR4
SCHEMBL8888466 0.98 LTA4H (0.87) LTA4HEPHX2BCHEFFAR1FFAR4
SCHEMBL1563277 0.95 LTA4H (1.00) LTA4HEPHX2BCHEFFAR1FFAR4
SCHEMBL11687518 0.93 LTA4H (0.97) LTA4HEPHX2BCHEFFAR1FFAR4
SCHEMBL14300868 0.90 LTA4H (0.90) LTA4HEPHX2BCHEFFAR1FFAR4
SCHEMBL12040562 0.89 LTA4H (0.77) LTA4HEPHX2BCHEFFAR1FFAR4
SCHEMBL12630258 0.89 LTA4H (0.77) LTA4HEPHX2BCHEFFAR1FFAR4
SCHEMBL5700 0.87 LTA4H (0.80) LTA4HEPHX2BCHEFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398168-B2 Preparation method of a glycoside compound SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) 2025-08-26 US disclosed
CN-111961006-B Method for synthesizing intermediate of trilithiotinib triazole 同济大学 2023-03-28 CN disclosed
US-20220380399-A1 PREPARATION METHOD OF A GLYCOSIDE COMPOUND SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) 2022-12-01 US disclosed
WO-2021139621-A1 METHOD FOR PREPARING GLYCOSIDE COMPOUND 上海和黄药业有限公司 2021-07-15 WO disclosed
CN-111961006-A Method for synthesizing intermediate of trilithiotinib triazole 同济大学 2020-11-20 CN disclosed
EP-1270571-B1 Heterocyclic compounds, their production and use TAKEDA PHARMACEUTICAL (JP) 2006-09-06 EP disclosed
US-7019172-B2 Process for preparation of S-(-)-betaxolol and salts thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-03-28 US disclosed
US-20060004109-A1 Cyclopropanating 1-(2-allyloxyethyl)-4-benzyloxybenzene by the Simmon-Smith reaction with Furukawa modification to obtain the enantiomer 1-benzyloxy-4-(2-cyclopropyl methoxyethyl)benzene of high purity; avoiding the use of highly lacrymatric and unstable cyclopropylmethyl halide COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-01-05 US disclosed
US-20040138160-A1 Preventive/therapeutic method for cancer TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-07-15 US disclosed
US-20040116330-A1 Diagnosing or specifying a growth factor receptor expressed in cancer cells, and selectively inhibiting all or a part of the growth factor receptor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-06-17 US disclosed
EP-0512065-A4 APPARATUS AND METHOD FOR IONTOPHORETIC TRANSFER 1992-12-30 EP disclosed
EP-0512065-A1 APPARATUS AND METHOD FOR IONTOPHORETIC TRANSFER GENSIA PHARMACEUTICALS, INC. (US) 1992-11-11 EP disclosed
US-5124070-A High speed response SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-23 US disclosed
US-5108363-A DIAGNOSIS, EVALUATION AND TREATMENT OF CORONARY ARTERY DISEASE BY EXERCISE SIMULATION USING CLOSED LOOP DRUG DELIVERY OF AN EXERCISE SIMULATING AGENT BETA AGONIST GENSIA PHARMACEUTICALS, INC. (US) 1992-04-28 US disclosed
US-5088978-A APPARATUS AND METHOD FOR IONTOPHORETIC TRANSFER GENSIA PHARMACEUTICALS, INC. (US) 1992-02-18 US disclosed
WO-1991011215-A1 APPARATUS AND METHOD FOR IONTOPHORETIC TRANSFER GENSIA PHARMACEUTICALS, INC. (US) 1991-08-08 WO disclosed
EP-0357372-A2 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed
EP-0329464-A2 System for the closed-loop administration of an exercise simulating agent GENSIA, INC. (US) 1989-08-23 EP disclosed
US-4761420-A CARDIOVASCULAR DISORDERS LABORATOIRES SYNTEX S.A. (FR) 1988-08-02 US disclosed
EP-0249245-A2 Antihypertensive dihydropyridine derivatives LABORATOIRES SYNTEX S.A. (FR) 1987-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12398168-B2 Preparation method of a glycoside compound GALE, ST6GAL1, MGAM LTA4H 887/4885EPHX2 308/4885BCHE 344/4885
US-20060004109-A1 Cyclopropanating 1-(2-allyloxyethyl)-4-benzyloxybenzene by the Simmon-Smith reaction with Furukawa modification to obtain the enantiomer 1-benzyloxy-4-(2-cyclopropyl methoxyethyl)benzene of high purity; avoiding the use of highly lacrymatric and unstable cyclopropylmethyl halide SMAD2, SPHK1, TGFBR1 LTA4H 519/4885EPHX2 866/4885BCHE 2329/4885
US-20220380399-A1 PREPARATION METHOD OF A GLYCOSIDE COMPOUND GALE, ST6GAL1, MGAM LTA4H 887/4885EPHX2 308/4885BCHE 344/4885
US-20040138160-A1 Preventive/therapeutic method for cancer EGFR, ERBB2, ERBB3 LTA4H 3586/4885EPHX2 1905/4885BCHE 2980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.