Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8887790 | 0.99 | HPGD (0.54) | HPGDRECQLKDM4EHSD17B10CA1 | |
| SCHEMBL8888568 | 0.83 | HPGD (0.53) | HPGDRECQLKDM4EHSD17B10CA1 | |
| Hydrochloric Acid SCHEMBL8887479 | 0.82 | KMT2A (0.58) | HPGDKDM4ECA1CA2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8887795 | 0.82 | HPGD (0.52) | HPGDRECQLKDM4EHSD17B10CA1 | |
| SCHEMBL8887638 | 0.82 | PTGER4 (0.64) | HPGDRECQLKDM4EHSD17B10CA1 | |
| SCHEMBL2348503 | 0.81 | NEU3 (0.60) | HPGDKDM4EHSD17B10SMN1; SMN2PTGER4 | |
| SCHEMBL13530949 | 0.81 | RAB9A (0.53) | KDM4ECA1CA2SMN1; SMN2PTGER4 | |
| SCHEMBL8959050 | 0.80 | HPGD (0.62) | HPGDRECQLKDM4EHSD17B10CA1 | |
| SCHEMBL8959046 | 0.80 | HPGD (0.67) | HPGDRECQLKDM4EHSD17B10CA1 | |
| Hydrochloric Acid SCHEMBL8889341 | 0.79 | ALDH1A1 (0.50) | HPGDKDM4ECA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |