Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | HRH2 | P25021 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907370 | 0.91 | ITGB3 (0.47) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL9089274 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL9089268 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL9089276 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL11455855 | 0.77 | ITGB3 (0.56) | ITGB3ITGA2BHRH1HRH2PTPN1 | |
| SCHEMBL9081854 | 0.77 | ITGB3 (0.51) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL11370281 | 0.76 | ITGB3 (0.55) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL27757441 | 0.76 | ITGB3 (0.61) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL11368691 | 0.76 | ITGB3 (0.55) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL27757439 | 0.76 | ITGB3 (0.61) | ITGB3ITGA2BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652242-A | 3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL)PHENOXY)BURYIC ACID, AMIDE OR ESTER; INHIBITORS OF BINDING OF FIBRINOGEN TO GLYCOPROTEIN | ZENECA LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| US-5556977-A | ANTIAGGLOMERANTS FOR CELLS, ANTICOAGULANTS, ANTIISCHEMIC AGENTS USING PYRIDINYLPIPERAZINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |