Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.45 |
| ▸ | HRH1 | P35367 | 5/20 | 0.44 |
| ▸ | HRH2 | P25021 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889083 | 0.91 | ITGB3 (0.50) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7329340 | 0.79 | YAP1 (0.50) | ITGB3ITGA2BHRH1HRH2 | |
| SCHEMBL7329334 | 0.79 | YAP1 (0.50) | ITGB3ITGA2BHRH1HRH2 | |
| SCHEMBL9080518 | 0.79 | ITGB3 (0.54) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL21301659 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BHRH1HRH2 | |
| SCHEMBL1834332 | 0.79 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL1834331 | 0.79 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL11456532 | 0.78 | HRH2 (0.53) | ITGB3ITGA2BHRH1HRH2 | |
| SCHEMBL9080305 | 0.77 | ITGB3 (0.48) | ITGB3ITGA2BHRH3HRH1 | |
| SCHEMBL9080299 | 0.76 | ITGB3 (0.55) | ITGB3ITGA2BHRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652242-A | 3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL)PHENOXY)BURYIC ACID, AMIDE OR ESTER; INHIBITORS OF BINDING OF FIBRINOGEN TO GLYCOPROTEIN | ZENECA LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |