Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889113 | 0.87 | CYP1A2 (0.50) | PTGIRCYP1A2MEN1KMT2ACRHBP | |
| SCHEMBL8890203 | 0.84 | CYP1A2 (0.47) | PTGIRCYP1A2MAPTPDE4APDE4B | |
| SCHEMBL8888651 | 0.82 | CYP1A2 (0.55) | CYP1A2MEN1KMT2AMAPTPDE5A | |
| SCHEMBL8887697 | 0.82 | CYP1A2 (0.47) | PTGIRCYP1A2MEN1KMT2APDE4A | |
| SCHEMBL8889588 | 0.81 | CYP1A2 (0.49) | PTGIRCYP1A2MEN1KMT2ACYP2C9 | |
| SCHEMBL8887601 | 0.77 | LMNA (0.48) | CYP1A2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL5807524 | 0.74 | CYP1A2 (0.51) | CYP1A2MEN1KMT2APDE5APDE3A | |
| SCHEMBL8889716 | 0.74 | PDE4A (0.52) | CYP1A2MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL5810373 | 0.70 | CYP1A2 (0.41) | CYP1A2KMT2APDE5APDE3A | |
| SCHEMBL8888843 | 0.70 | MEN1 (0.53) | PTGIRCYP1A2MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |